Miniaturized Aptamer-Based Assays for Protein Detection
نویسندگان
چکیده
منابع مشابه
Miniaturized Aptamer-Based Assays for Protein Detection
The availability of devices for cancer biomarker detection at early stages of the disease is one of the most critical issues in biomedicine. Towards this goal, to increase the assay sensitivity, device miniaturization strategies empowered by the employment of high affinity protein binders constitute a valuable approach. In this work we propose two different surface-based miniaturized platforms ...
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BACKGROUND DNA aptamers are single-stranded nucleotide sequences that bind specifically to target molecules. By combining the advantages of PCR for amplifying specific DNA sequences and aptamer technology, we have developed a new strategy to detect target molecules such as proteins. METHODS Ovine follicle-stimulating hormone alpha subunit (oFSHalpha) was used as the model protein to generate ...
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ژورنال
عنوان ژورنال: Chemosensors
سال: 2016
ISSN: 2227-9040
DOI: 10.3390/chemosensors4030018